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virtual library in human genetics and molecular biology

Research Papers

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
J. Alan Diehl, Frederique Zindy, and Charles J. Sherr 957

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development
Yimin Yan, Jonas Frisén, Mong-Hong Lee, Joan Massagué, and Mariano Barbacid 973

The TGF-ß family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
Marcus Kretzschmar, Fang Liu, Akiko Hata, Jacqueline Doody, and Joan Massagué 984

Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation
Gürkan Kaya, Ivan Rodriguez, Jose L. Jorcano, Pierre Vassalli, and Ivan Stamenkovic 996

The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle
Jia-Ching Shieh, Marc G. Wilkinson, Vicky Buck, Brian A. Morgan, Kozo Makino, and Jonathan B.A. Millar 1008

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
Hosung Min, Christoph W. Turck, Julia M. Nikolic, and Douglas L. Black 1023

A shared subunit belongs to the eukaryotic core RNA polymerase
Martin Lanzendörfer, Amke Smid, Corinne Klinger, Patrick Schultz, André Sentenac, Christophe Carles, and Michel Riva 1037

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
Chay T. Kuo, Edward E. Morrisey, Roshani Anandappa, Kirsten Sigrist, Min M. Lu, Michael S. Parmacek, Claire Soudais, and Jeffrey M. Leiden 1048

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
Jeffery D. Molkentin, Qing Lin, Stephen A. Duncan, and Eric N. Olson 1061

mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye
Helen McNeill, Chung-Hui Yang, Michael Brodsky, Josette Ungos, and Michael A. Simon 1073

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