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virtual library in human genetics and molecular biology

Review

Protein quality control: triage by chaperones and proteases
Susan Gottesman, Sue Wickner, and Michael R. Maurizi 815



Research Papers

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction
Chan R. Beals, Neil A. Clipstone, Steffan N. Ho, and Gerald R. Crabtree 824

Stoichiometric and steric principles governing repression by nuclear hormone receptors
Iris Zamir, Jinsong Zhang, and Mitchell A. Lazar 835

New functional activities for the p21 family of CDK inhibitors
Joshua LaBaer, Michelle D. Garrett, Lauren F. Stevenson, Joyce M. Slingerland, Charanjit Sandhu, Hubert S. Chou, Ali Fattaey, and Ed Harlow 847

UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior
Giovanni Cenci, Robert B. Rawson, Giorgio Belloni, Diego H. Castrillon, Mark Tudor, Romano Petrucci, Michael L. Goldberg, Steven A. Wasserman, and Maurizio Gatti 863

The meiotic recombination hot spot created by the single-base substitution ade6-M26 results in remodeling of chromatin structure in fission yeast
Ken-ichi Mizuno, Yukihiro Emura, Michel Baur, Jürg Kohli, Kunihiro Ohta, and Takehiko Shibata 876

Distinct roles for P-CREB and LEF-1 in TCRalpha enhancer assembly and activation on chromatin templates in vitro
Timothy P. Mayall, Philip L. Sheridan, Marc R. Montminy, and Katherine A. Jones 887

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns
Alex Gould, Alastair Morrison, Graham Sproat, Robert A.H. White, and Robb Krumlauf 900

Anemia and perinatal death result from loss of the murine ecotropic retrovirus receptor mCAT-1
Christopher P. Perkins, Vernon Mar, John R. Shutter, Juan del Castillo, Dimitry M. Danilenko, Eugene S. Medlock, Ian L. Ponting, Melissa Graham, Kevin L. Stark, Yi Zuo, James M.
Cunningham, and Robert A. Bosselman 914

The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo
Glenn E. Winnier, Linda Hargett, and Brigid L.M. Hogan 926

The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation
Philippe Ganot, Michèle Caizergues-Ferrer, and Tamás Kiss 941

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