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virtual library in human genetics and molecular biology

Reviews

Mouse models of human disease. Part I: Techniques and resources for genetic analysis in mice
Mary A. Bedell, Nancy A. Jenkins, and Neal G. Copeland 1

Mouse models of human disease. Part II: Recent progress and future directions
Mary A. Bedell, David A. Largaespada, Nancy A. Jenkins, and Neal G. Copeland 11



Research Papers

Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites
Peter J. Hurlin, Christophe Quéva, and Robert N. Eisenman 44

Suprabasal expression of a dominant-negative RXR-alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids
Xu Feng, Zhen-Hui Peng, Wen Di, Xiao-Yan Li, Cécile Rochette-Egly, Pierre Chambon, John J. Voorhees, and Jia-Hao Xiao 59

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
Hui Tian, Steven L. McKnight, and David W. Russell 72

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
Sabine Strahl-Bolsinger, Andreas Hecht, Kunheng Luo, and Michael Grunstein 83

Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A
Xinzhong Dong, Kenton H. Zavitz, Barbara J. Thomas, Michael Lin, Shelagh Campbell, and S. Lawrence Zipursky 94

Meiotic cells monitor the status of the interhomolog recombination complex
Liuzhong Xu, Beth M. Weiner, and Nancy Kleckner 106

Biochemical characterization of a molecular switch involving the heat shock protein ClpC, controls the activity of ComK, the competence transcription factor of Bacillus subtilis
Kürsad Turgay, Leendert W. Hamoen, Gerard Venema, and David Dubnau 119

The alternative splicing factor PSI regulates P-element third intron splicing in vivo
Melissa D. Adams, Rosa S. Tarng, and Donald C. Rio 129

A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor
David S. Horowitz and Adrian R. Krainer 139

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