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Review
From screens to genes: prospects for insertional mutagenesis in zebrafish Alexander F. Schier, Alexandra L. Joyner, Ruth Lehmann, and William S. Talbot 3077
Research papers
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p Orna Cohen-Fix, Jan-Michael Peters, Marc W. Kirschner, and Doug Koshland 3081
Est1 has the properties of a single-stranded telomere end-binding protein Valerie Virta-Pearlman, Danna K. Morris, and Victoria Lundblad 3094
Glucose regulates protein interactions within the yeast SNF1 protein kinase complex Rong Jiang and Marian Carlson 3105
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing Tatsuhiko Kadowaki, Elizabeth Wilder, John Klingensmith, Kimon Zachary, and Norbert Perrimon 3116
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system Karl K. Johe, Thomas G. Hazel, Thomas Muller, Millicent M. Dugich-Djordjevic, and Ronald D.G. McKay 3129
Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development Miguel L. Allende, Adam Amsterdam, Thomas Becker, Koichi Kawakami, Nicholas Gaiano, and Nancy Hopkins 3141
Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis Erik Bonten, Aarnoud van der Spoel, Maarten Fornerod, Gerard Grosveld, and Alessandra d'Azzo 3156
SurA, a periplasmic protein with peptidyl-prolyl isomerase activity, participates in the assembly of outer membrane porins Pierre E. Rouvière and Carol A. Gross 3170
Segmentation and specification of the Drosophila mesoderm Natalia Azpiazu, Peter A. Lawrence, Jean-Paul Vincent, and Manfred Frasch 3183
The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo Jumin Zhou, Scott Barolo, Paul Szymanski, and Michael Levine 3195
Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex Kirsten Hagstrom, Martin Muller, and Paul Schedl 3202
Corrigendum 3216
Product News 3217
Reviewers, Volume 10 3219
Advertisers, Volume 10 3222
Author Index, Volume 10 3223
Subject Index, Volume 10 3227
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