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virtual library in human genetics and molecular biology

Review

Strange bedfellows in even stranger places: the role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53
R. Scott Hawley and Stephen Friend 2383

Research papers

Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization
Neil Segil, Mohamed Guermah, Alexander Hoffmann, Robert G. Roeder, and Nathaniel Heintz 2389

Dual roles of ATM in the cellular response to radiation and in cell growth control
Yang Xu and David Baltimore 2401

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
Yang Xu, Terry Ashley, Elizabeth E. Brainerd, Roderick T. Bronson, M. Stephen Meyn, and David Baltimore 2411

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes
Kathleen S. Keegan, Douglas A. Holtzman, Annemieke W. Plug, Erik R. Christenson, Elizabeth E. Brainerd, Gail Flaggs, Nicola J. Bentley, Elaine M. Taylor, M. Stephen Meyn, Stuart B. Moss, Antony M. Carr, Terry Ashley, and Merl F. Hoekstra 2423

p53 Levels, functional domains, and DNA damage determine the extent of apoptotic response of tumor cells
Xinbin Chen, Linda J. Ko, Lata Jayaraman, and Carol Prives 2438

Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor
Matthias Hammerschmidt, George N. Serbedzija, and Andrew P. McMahon 2452

TGF-beta 1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
Martin Oft, Janos Peli, Claude Rudaz, Heinz Schwarz, Hartmut Beug, and Ernst Reichmann 2462

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation
Richard Eckner, Tso-Pang Yao, Elizabeth Oldread, and David M. Livingston 2478

Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo
Gene O. Bryant, Lisa S. Martel, Stephen K. Burley, and Arnold J. Berk2491

E2F-induced S phase requires cyclin E
Robert J. Duronio, Adam Brook, Nicholas Dyson, and Patrick H. O'Farrell 2505

The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion
Mary A. Lilly and Allan C. Spradling 2514

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