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2/12 Ak.Timakov Str.
Novosibirsk 630117
Russia Phone: 7 383 3334991 Fax: 7 383 3336853
Description:
SibEnzyme Ltd. (Siberian Enzyme, SE) is a privately owned Russian biotechnology company founded in 1991 and located in Akademgorodok, Novosibirsk — one of Russia’s leading centers of science and biotechnology. SibEnzyme specializes in the research, development, and manufacture of enzymes and related products for molecular biology, genetic engineering, genomics, and epigenetics. The company’s product portfolio includes more than 200 enzymes, among them restriction endonucleases, methyl-directed DNA endonucleases, DNA nickases, DNA methyltransferases, polymerases, ligases, and other DNA-modifying enzymes. The catalogue also includes DNA ladders, dNTPs, DNA preparations, buffers, and molecular biology kits. A major area of SibEnzyme’s expertise is the discovery and characterization of novel and rare restriction endonucleases. Many enzymes in the company’s catalogue were originally discovered, characterized, cloned, or developed by SibEnzyme scientists. The company has also contributed to the discovery of site-specific DNA nickases and a novel class of 5-methylcytosine-directed DNA endonucleases. The Turbo line of restriction endonucleases provides rapid DNA digestion in 5–15 minutes using a unified protocol and the ROSE reaction buffer. SibEnzyme continues to expand this line with both widely used and unique enzymes. Another important research area is epigenetic analysis. SibEnzyme develops methylation-sensitive enzymes and enzyme-based methods for DNA methylation detection, including the GLAD-PCR assay, which enables site-specific methylation analysis without bisulfite conversion. The SibEnzyme team brings together highly qualified scientists with decades of experience in enzymology, molecular biology, and biotechnology. The company collaborates with research institutions in Akademgorodok and Novosibirsk State University, combining fundamental research with the development of practical tools for life-science laboratories. SibEnzyme operates an ISO 9001:2015-certified quality management system and supplies its products to research, educational, biotechnology, and pharmaceutical organizations. Website: https://www.sibenzyme.com
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Last update of this entry: July 16, 2026
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