PREMIER Biosoft Bioinformatics Company

3786 Corina Way
Palo Alto, CA 94303, USA
United States of America, California

Phone: 001-650-856-2703
Fax: 650-618-1773
E-Mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Please notice: This entry hasn't been updated by the submitting company for more than 2 years. It could be possible that this company doesn't longer exists.

Description:

PREMIER Biosoft is a Palo Alto (CA) based molecular biology software authoring and marketing company and has been developing tools for life science researchers and molecular biologists since 1994. PREMIER Biosoft International is dedicated to bringing intuitive software tools to the life science research community. We have tools for real time PCR primer design, design of TaqMan probes, PCR primer design, bacterial identification, detecting gene splicing, SNP detection and tissue microarray data analysis

Products:

Bacterial identification using real time PCR primer design:

AlleleID is the only design tool that designs probes and primers for pathogen detection, bacterial identification, species identification and cross species research using real time PCR and microarray assays . One can align sequences to locate differences in DNA and to find conserved regions. Then proceed to design oligos to amplify and detect only the species or strains of interest from the mix. To design taxa specific or cross species assays, design the least number of oligos to identify a group of genes of interest. AlleleID also supports assays for selectively amplifying cDNA from gDNA. You can use AlleleID to detect alternative splicing using microarray based experiments. AlleleID can design allele specific oligonucleotide primers and probes for allele identification

Oligo Design for High Throughput SNP Genotyping, SNP Analysis

PrimerPlex designs oligos for multiplex analysis on suspension array systems such as Luminex 100, Luminex 200 and Bio-Plex 200. Based on Luminex xMAP® technology, these systems offer a platform for multiplex nucleic acid detection. PrimerPlex designs capture probes for direct hybridization assays and primer pairs for Allele Specific Primer Extension.

Singleplex and multiplex real time PCR assay design

Beacon Designer designs oligos for real time PCR assays viz. SYBR® Green primers, TaqMan® probes, LNA spiked TaqMan®, molecular beacons, NASBA® and FRET probes. Highly specific primers are designed by avoiding cross homologies found by automatically interpreting BLAST search results. Beacon Designer can be used to evaluate pre-designed assays and designing compatible oligos to extend the designs. It can design beacons and TaqMan® for single tube multiplex experiments. The version 6 of Beacon Designer includes support for identifying patterns in DNA methylation by automatically interpreting CpG islands and designing TaqMan® based MethyLight assays. Beacon Design can be regarded as a complete qPCR or real time PCR design tool.

SimGlycan matches the MS/MS spectra with its own comprehensive, robust and annotated database to predict & analyze the structure of the glycan. It generates a list of all probable glycans saving time, money and the frustration of laborious work. Each structure is scored to help judge which results closely match the experimental data. Alongside the probable glycan structure important information such as the glycan class, reaction, pathway and enzyme is also made available. SimGlycan is used by researchers to study glycosylation and other post translational modifications.

TMA Foresight: It is a tissue microarray software that analysis tissue microarray data and identifies significant prognostic markers.

NetPrimer: A free online primer analysis and design software

Microarray software for microarray gene expression studies and SNP detection

Array Designer can design efficient, specific oligos for SNP genotyping and gene expression profiling. Start with a list of sequences or the whole genome sequence to study entire organisms effortlessly. Array Designer automatically interprets BLAST results to design specific oligos. Design tiling arrays by avoiding repetitive regions, spot every base of a genomic sequence, to characterize regulatory elements, or to study epigenetic modifications, methylation patterns or protein binding sites. Or design resequencing arrays, far less expensive than the capillary or dideoxy sequencing alternatives, for rapid and accurate populations genotyping studies.

Primer Premier: Primer Premier is a program for PCR, hybridization, sequencing, nested and multiplex primer design. It uses ClustalW multiple sequence alignment to design cross species primers automatically in regions of low degeneracy. Primer Premier reverse translates amino acid sequences to design degenerate primers. Designing allele specific primers and primers for site-directed mutagenesis is made easy. Sequences can be analyzed for restriction enzymes and motifs using extensive built-in databases.

SimVector:SimVector is a web savvy Windows and Mac program equipped with all the drawing tools necessary to publish engineered plasmid catalogs, as well as to simulate and draw plasmid maps for Gateway®, TA, Restriction or other popular cloning techniques. Export images in vector graphic format to produce the highest quality images for presentations via MS PowerPoint or publication in journals or vector catalogs via Adobe Illustrator 10. Alternatively, choose popular bitmap formats or export in ready-to-host web pages. With its powerful and intuitive drawing features, it is easy to enhance vector maps with patterns, colors, fills,curved text and annotations.

Xpression Primer:Xpression Primer is a web savvy Windows and Mac program with a sophisticated algorithm for designing optimal tagged primers to amplify ORFs for expression cloning systems. It provides comprehensive support for popular systems such as Gateway®, BD In-Fusion?, epitope and TOPO® tools. The program is flexible enough to work with virtually any expression system of researcher's choice. Xpression Primer also designs optimal sequencing primers to verify the transcripts.

Last update of this entry: February 11, 2009