news archive genetic news - June 4, 2009

June 4, 2009

your information resource in human molecular genetics

-	Listen Up: Focus on Hearing Seven perspective and review articles cover recent advances in our understanding of how sounds are converted into neural signals, how these processes go wrong in hearing loss, and what attempts to rectify such hearing loss tell us about brain function.
-	Suppressing Suppressors The discovery of an inhibitory signaling circuit that blocks the generation and function of regulatory T cells is reported.
-	Genome Scan Uncovers Genetic Risks of Testis Cancer Gene variants accounting for some of the differences between men in their risk of developing testis cancer have been identified.
-	Genetic Variation Influences Adverse Reaction to Common Antibiotic A common genetic difference between people influences their chance of developing a rare but serious liver injury as a side effect of taking the antibiotic flucloxacillin.
-	How Do Inhibitors Activate Kinases? Inhibitor binding leads to pre-activation of two kinases.
-	Targeting Muscle Disorders A molecular link between the loss of function of the enzyme MIP/MTMR14 and the muscle defects in mice is reported.
-	Genetic Reprogramming Researchers have generated stem cells from patients with a rare genetic disease, corrected the cells' defect and reprogrammed to pluripotency.
-	DNA Genie Bottle Assembles Itself A variety of complex self-assembled DNA shapes are revealed.
-	How Down's Syndrome Protects A genetic explanation for why people with Down's syndrome have a reduced incidence of solid cancers.
-	Nature Precedings: A preprint server for biomedical sciences A new online platform for the posting and sharing of preliminary findings and preprints