home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Genome Scan Uncovers Genetic Risks of Testis Cancer

  June, 4 2009 8:22
your information resource in human molecular genetics

Gene variants accounting for some of the differences between men in their risk of developing testis cancer have been identified according to two studies published online in Nature Genetics.

Testicular germ cell tumor is the most common malignancy in men between the ages of 15 and 45 years and is five times more common in men of European ancestry than in those of African ancestry. To find gene variants associated with risk of this disease, Michael Stratton, Katherine Nathanson and colleagues examined thousands of men of European ancestry in the UK and US.

One of the risk-associated genes they found -- KITLG -- also confers differences in skin and hair color. Since KITLG risk variants are more common in populations with recent European origins than in those with recent African origins, these genetic differences may explain some of the population differences in the incidence of the disease.

Author Contacts:

For Michael Stratton, please contact Jane Bunce (Senior Press Officer, The Institute of Cancer Research)
E-mail: jane.bunce@icr.ac.uk

For Katherine Nathanson, please contact Holly Auer (Senior Medical Communications Officer, University of Pennsylvania, Philadelphia, PA, USA)
E-mail: holly.auer@uphs.upenn.edu

Abstracts available online:
Abstract 1.
Abstract 2.

(C) Nature Genetics press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.