news archive genetic news - November 16, 2005

November 16, 2005

your information resource in human molecular genetics

-	Getting Lymphocytes Going Scientists report that 'microclusters' of molecules are the discrete physical structures required for triggering and, importantly, sustaining immune signals.
-	Allergy Safety Pins Researchers identify the enzyme Pin1 that increases the stability of mRNAs encoding GM-CSF.
-	Heart Risk From Inflammmatory Gene Variant A common variant of a gene involved in inflammation is 3.57 times more common in African American individuals who have had a heart attack than in African Americans who have not.
-	Small-Molecule Suppressor Research paper reports a small molecule that suppresses the phenotype of a zebrafish mutation.
-	Skeletons In Cancer's Closet Scientists have found the mechanism of action of a natural product known to be toxic to cancer cells.
-	Agonizing Over CD40 A new approach to targeting cellular receptors in the immune system using small molecules.
-	A Path To Beating Cancer Two studies report promising developments in promoting more targeted and effective cancer treatment regimes in the future.
-	Mitochondrial Import And Enzymatic Activity Of PINK1 Mutants Associated To Recessive Parkinsonism Study describes effects of mutations to a putative mitochondrial kinase, PINK1, as well as mitochondrial localization of the wild-type and mutant PINK1 proteins.
-	Multiple Mutations In Mouse Chd7 Provide Models For CHARGE Syndrome Study finds widespread expression of Chd7 in early development of the mouse in organs affected in CHARGE syndrome.
-	Cannabinoid Receptor Type 2 Gene Is Associated With Human Osteoporosis The results provide an interesting novel therapeutical target for this severe and common disease.
-	Novel Discovery Of 'DCDC2' Gene Associated With Dyslexia DCDC2 is associated with reading disability and modulates neuronal development in the brain.
-	Forgotten by evolution? Adult Stem Cells May Be Just Remnants Of Evolution