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news archive genetic news - May 17, 2005

 
  May 17, 2005
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- Disentangling Fetal And Maternal Susceptibility For Pre-Eclampsia
The Genetics of Pre-Eclampsia (GOPEC) collaboration aims to identify genetic factors in U.K. families affected by pre-eclampsia.
- Allan-Herndon-Dudley Syndrome and the Monocarboxylate Transporter 8 (MCT8) Gene
Disturbances in blood levels of thyroid hormones suggest the possibility of systematic detection through screening of high-risk populations.
- Mapping Of A Single Locus Capable Of Complementing The Defective Heterochromatin Phenotype Of RS Cells
Complementation of this abnormal cytogenetic phenotype was used as a means to identify a specific region of the normal human genome capable of rendering phenotypic correction.
- Brain Changes Over The Menstrual Cycle
Report may provide a molecular basis for some of the hormonal fluctuations over the course of the menstrual (or estrus) cycle.
- Race-Related Brain Activity
Report shows that the brain area called the amygdale, that is involved in emotional processing, is activated in response to pictures of same-race faces.
- Wiring The Brain For Depression
Healthy carriers of a gene that increases the risk of depression have altered activity in brain circuits involved in emotion.
- Human Trial Shows Potential And Limitations Of Anti-HIV Antibodies
A clinical trial in a small group of HIV-1 infected patients has provided the first direct proof in humans that antibodies can control the virus -- but only for a very short time.
- Stiff Handling Of Genes
The efficacy of materials for carrying genes into cells may be determined more by their stiffness than by their chemical properties.
- Bacterial Trojan Horses
New work identifies an important molecule to target against Brucella infections in both humans and animals.
- RNA Enzymes Use Acid
Researchers show how a RNA molecule from the hepatitis delta virus (HDV) uses an acidic group to accelerate a chemical reaction central to its life cycle.
- Fat: The Big Picture
Research identifies the network of genes required for early steps in the development of brown fat cells.
- Molecule That Induces Tumour Regression
A promising approach to eliminate cancer cells is to trigger cell death (apoptosis) with inhibitors that bind to and block anti-apoptotic proteins that help keep cancer cells alive.
- Interactions Between Separate Chromosomes Might Control Gene Expression
Physical interaction between chromosomes might play an important role in coordinating gene expression in the nucleus of higher organisms.
- Insulin Triggers Autoimmune Response In Diabetes
Two groups of researchers provide convincing proof that insulin itself initiates the devastating autoimmune response associated with Type I Diabetes.
- New Disease/Phenotype Technical Standards And Guidelines Now Available On-Line
Prenatal Screening for Down Syndrome, Open Neural Tube Defects, Venous Thromboembolism
- ACMG's Revised Guidelines For Cystic Fibrosis Population Carrier Testing
Link to free copy of the guidelines is provided in this posted summary.

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