The GOPEC Consortium
Described are the results of extensive genotyping of seven candidate genes previously reported as conferring susceptibility to pre-eclampsia.
The authors conclude that none of the genetic variants tested in this large study of strictly defined pre-eclamptic pregnancies confers a high risk of disease.
The results emphasize the importance of conducting rigorously designed studies of adequate size to provide precise genetic risks with narrow confidence intervals, if overreporting of false-positive results is to be avoided.
Abstract of this article can be accessed here.
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