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The role of cancer-causing mutations in BRCA1
Two structural studies reveal how such mutations can affect the function of BRCA1, leading to cancer.
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Insulin factories produced by self replication
Insulin-producing beta-cells can proliferate by making more of themselves, according to a study, which counters the prevailing hypothesis on beta-cell production, and may aid the development of new treatments for type I diabetes.
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Genetic trigger for heart attack
A single base mutation in a key gene may affect an individual's susceptibility to heart attack.
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DNA computers could control gene expression
Researchers have made a tiny molecular-scale computer that can analyse biological information in a test tube and respond appropriately.
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Tracking cancer treatments
A new way of studying the action of a breast-cancer drug in the body promises to facilitate the design of molecular-targeted therapies.
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Enhancing incorporation of stem cells
Research shows that bone marrow stem cells from mice, missing a gene known to inhibit cell division, can overcome the hurdle of inducing efficient repopulation of target tissues by stem cells.
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New insights into male infertility
A protein important for defence against pathogens may also be required for sperm maturation, suggesting a possible common basis for some sexually transmitted diseases (STDs) and infertility.
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