news archive genetic news - May 11, 2004

May 11, 2004

your information resource in human molecular genetics

-	The role of cancer-causing mutations in BRCA1 Two structural studies reveal how such mutations can affect the function of BRCA1, leading to cancer.
-	Insulin factories produced by self replication Insulin-producing beta-cells can proliferate by making more of themselves, according to a study, which counters the prevailing hypothesis on beta-cell production, and may aid the development of new treatments for type I diabetes.
-	Genetic trigger for heart attack A single base mutation in a key gene may affect an individual's susceptibility to heart attack.
-	DNA computers could control gene expression Researchers have made a tiny molecular-scale computer that can analyse biological information in a test tube and respond appropriately.
-	Tracking cancer treatments A new way of studying the action of a breast-cancer drug in the body promises to facilitate the design of molecular-targeted therapies.
-	Enhancing incorporation of stem cells Research shows that bone marrow stem cells from mice, missing a gene known to inhibit cell division, can overcome the hurdle of inducing efficient repopulation of target tissues by stem cells.
-	New insights into male infertility A protein important for defence against pathogens may also be required for sperm maturation, suggesting a possible common basis for some sexually transmitted diseases (STDs) and infertility.