home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Controlling The Enemy Within

  December, 6 2006 9:56
your information resource in human molecular genetics
The constant presence of a population of 'regulatory' immune cells is essential for the prevention of autoimmune disease, according to a paper published in the February 2007 issue of Nature Immunology.

Other strategies to impede autoimmunity exist, but whether they could maintain a healthy immune system in the absence of such 'regulatory' cells is not clear.

Alexander Rudensky and colleagues devised a way to rapidly deplete adult mice of regulatory immune cells called T regulatory (Treg) cells. Shortly after Treg cell depletion, immune cells traveled to and began damaging internal organs. All mice succumbed to that fatal autoimmune attack within 4 weeks of Treg cell depletion.

These results emphasize that Treg cell function is more critical than other strategies for keeping potentially harmful cells in check.

Author contact:

Alexander Rudensky (University of Washington, Seattle, WA, USA)
E-mail: aruden@u.washington.edu

Abstract available online.

(C) Nature Immunology press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2018 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.