Single virus tracing sets the stage for new infection-fighting drugs and gene-therapy strategies.
A single virus, tagged with one fluorescent dye molecule, rapidly bumps against a living cell before suddenly being engulfed. Only a fraction of all single viruses make it past the external cell membrane, a Science study suggests. But, once inside, the virus has a good chance of penetrating its target, the nucleus, within a few minutes. Such insights may set the stage for better anti-viral drugs, or for delivering gene-therapy medicines directly to the cell nucleus.
American Association for the Advancement of Science
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