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Breast cancer susceptibility gene

 
  December, 8 2000 0:28
your information resource in human molecular genetics
 
     
Breast cancer susceptibility gene


Breast cancer is the most common cancer among
women, and the second leading cause of mortality from cancer. Mutations in the so-called breast cancer susceptibility gene, BRCA1, account for 40-50% of early onset familial breast cancer cases. Recently, scientists have discovered that the protein ATR is responsible for activating BRCA1 in response to UV light-induced DNA damage. This discovery provides the first evidence that ATR may be the newest breast cancer susceptibility gene.

Contact:
Nora Poppito
poppito@cshl.org
Cold Spring Harbor Laboratory


Message posted by: Wouter Kalle

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