|
|
|
A huge overview of genetic alterations in lung cancer is presented online in Nature. The study takes a new approach to analysing copy number changes in lung adenocarcinoma, identifying a gene that has a significant role in many of these tumours.
Matthew Meyerson and colleagues analyse a large collection of tumours and identify 31 recurrent focal events, including 24 amplifications and 7 deletions occurring on both alleles. A new candidate oncogene, NKX2-1, is shown to be significant in a large number of lung cancers. The results, when added to other such recent studies, illustrate the power of systematic copy-number analysis. Author contact: Matthew Meyerson (Dana-Farber Cancer Institute, Boston, MA, USA)
E-mail: matthew_meyerson@dfci.harvard.edu (C) Nature press release.
Message posted by: Trevor M. D'Souza
|
|
Variants Associated with Pediatric Allergic Disorder
Mutations in PHF6 Found in T-Cell Leukemia
Genetic Risk Variant for Urinary Bladder Cancer
Antibody Has Therapeutic Effect on Mice with ALS
Regulating P53 Activity in Cancer Cells
Anti-RNA Therapy Counters Breast Cancer Spread
Mitochondrial DNA Diversity
The Power of RNA Sequencing
‘Pro-Ageing' Therapy for Cancer?
Niche Genetics Influence Leukaemia
Molecular Biology: Clinical Promise for RNA Interference
Chemoprevention Cocktail for Colon Cancer
more news ...
|