home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Improved Detection Of Bladder Cancer

 
  November, 1 2007 1:57
your information resource in human molecular genetics
 
     
A new method for detecting bladder tumours will provide improvements for patients' treatment and a reduction in cancer recurrence rates. In a review article appearing online in Nature Clinical Practice Urology, J Alfred Witjes and Jude Douglass compare this method with traditional methods and suggest that it could also prove more cost-effective in the diagnosis and management of bladder cancer.

Bladder cancer detection is still not perfect - despite the introduction of urinary markers the recurrence of tumours remains high. It is thought that this is partly the result of tumour cells being left behind following surgery. Fluorescence cystoscopy offers better visualization of bladder tumours than the traditional method of white-light cystoscopy, facilitating a more complete removal of the tumours during surgery. Studies have also confirmed that more tumours are detected by this method leading to reduced recurrence rates.

The authors discuss two types of fluorescence cystoscopy in their comparison with traditional white-light cystoscopy: Hexaminolevulinate (HAL) and 5-aminolevulinic (ALA) fluorescence cystoscopy. They argue that HAL offers several advantages over ALA for cystoscopy in patients with suspected bladder tumours as it is easier to use and improves the visibility of tumours. They also point out that fluorescence cystoscopy is associated with a small increase in the number of false positives compared to the traditional white-light technique. Studies into methods of reducing the false positive rate with HAL are underway.

Author contact:

J Alfred Witjes (University Medical Centre, Nijmegen, Netherlands)
E-mail: f.witjes@uro.umcn.nl

Free article available online.

(C) Nature Clinical Practice Urology press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.