home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Stem Cell Research (Nature Supplement)

  November, 3 2001 5:53
your information resource in human molecular genetics

For this month's 'Insight' reviews supplement Nature has asked leading researchers to cut through the hype and explain the fundamentals of stem cell biology as they see it today.

Stem cells bridge the gulf between the fertilized egg that is our origin and the architecture that we become. They supply the cells that construct our adult bodies and, as we age, replenish worn-out, damaged and diseased tissues. They renew themselves, resisting the powerful pull towards differentiation that overcomes more prosaic cells. And, depending on the source, they have the potential to form one, many or all cell types of an organism.

Stem cell research has a history of more than 20 years, and has made some outstanding contributions to our understanding of blood-cell production and mouse embryology. But the field has been transformed in the past few years by successes achieved in culturing human embryonic stem cells — the building blocks for every tissue we comprise — and in manipulating their differentiation in vitro. More recently, excitement has been fuelled by controversial evidence that adult stem cells have a much higher degree of developmental potential than was previously imagined.

Scientists now face the formidable task of justifying all the attention by bringing stem cell therapies to the clinic. But this will demand a better understanding of stem cells at the molecular level and of how they behave in their biological context. The factors that maintain stem cells in a multipotent, proliferative state, or drive them to create differentiated daughter cells in vitro or in vivo, must be identified.


Jo Webber (Nature Press Office)
el +44 20 7843 4571
e-mail j.webber@nature.com


The future for stem cell research - R Lovell-Badge

The end of the beginning for pluripotent stem cells - P J Donovan & J Gearhart

Stem cells find their niche - A Spradling, D Drummond-Barbosa & T Kai

Stem cells, cancer, and cancer stem cells - T Reya, S J Morrison, M F Clarke & I L Weissman

The development of neural stem cells - S Temple

Stem cells in tissue engineering - P Bianco & P G Robey

Reprogramming of genome function through epigenetic inheritance - M A Surani

Ethical and social considerations of stem cell research - A McLaren

(C)Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.