There are thousands of papers in the field of genetic epidemiology; online screening tools are fundamental in this area in order to get perspectives of entire research fields in a short time. The Human Genome Epidemiology Network (HuGENet) has created a quite useful resource called HuGE Navigator, which is online and freely available. This knowledge base has been developed with the use of advanced tools for data retrieval and mining of PubMed records.
A recent paper in European Journal of Human Genetics describes one of its latest tools: HuGE watch. HuGE watch generates temporal patterns (by years) or spatial distributions (by countries) for several parameters of relevance, such as number of publications, number of investigators, number of diseases or number of genes. It is possible to delimitate it by categories or study types (genotype prevalence, gene-disease associations, meta-analysis, among others). HuGE watch is automatically connected to other useful tools in HuGE Navigator, such as Genopedia or Phenopedia.
This online tool can be helpful for the researchers and institutions exploring the temporal or spatial dynamics of genetic epidemiology for specific diseases or genes. After a quick exploration of it, it is evident that some regions/diseases/genes are clearly overrepresented in the current literature.
Author: Wei Yu, National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, USA. E-mail: firstname.lastname@example.org
Yu W, Wulf A, Yesupriya A, Clyne M, Khoury MJ, Gwinn M. HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time. Eur J Hum Genet. 2008 Sep;16(9):1155-8. Paper available online.
The HuGE Watch server is available at the HuGE Navigator website.
Message posted by: Diego Forero
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