Pluripotent adult stem cells have been derived from cells in adult human testis for the first time. The research, published online in Nature, follows a similar result in mice last year and brings the potential of cell generation for individual therapy a step closer.
Previous research has demonstrated that mouse neonatal and adult germline stem cells (GSCs) are pluripotent and possess properties of embryonic stem cells. Thomas Skutella and colleagues establish pluripotent adult GSCs from spermatogonial cells of adult human testis. They propose that it may be possible to derive human adult GSCs from testicular biopsies in order to generate cells for individual cell-based therapies.
Thomas Skutella (University of Tübingen, Baden-Wuerttemberg, Germany)
Abstract available online.
(C) Nature press release.
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