Predictive Genetic Testing for Hereditary Breast and Ovarian Cancer: Psychological Distress and Illness Representations 1 Year Following Disclosure
E Claes (1), G. Evers-Kiebooms (1, 3), L. Denayer (1) , M. Decruyenaere (1), A. Boogaerts (1), K. Philippe (1) and E. Legius (2)
(1) Psychosocial Genetics Unit, Center for Human Genetics, University of Leuven, Belgium
(2) Clinical Genetics Unit, Center for Human Genetics, University of Leuven, Belgium
(3) Psychosocial Genetics Unit, Center for Human Genetics, Herestraat 49, (B) 3000 Leuven, Belgium
This prospective study, published in the October 2005 issue of the Journal of Genetic Counseling (Vol. 14, No. 5, pp. 349-363), evaluates emotional functioning and illness representations in 68 unaffected women (34 carriers/34 noncarriers) 1 year after predictive testing for BRCA1/2 mutations when offered within a multidisciplinary approach. Carriers had higher subjective risk perception of breast cancer than noncarriers.
The study did not reveal adverse effects of predictive testing when offered in the context of a multidisciplinary approach.
Abstract available online.
(C) Journal of Genetic Counseling.
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