|
|
|
Does the proportion of non-protein-coding DNA scale with gene density, or are the two unrelated? With the completed map of human chromosome 18 - which has a particularly low density of genes - researchers have had a chance to address this question.
In the 22 September 2005 issue of Nature (Vol. 437, No. 7058, pp 551-555), Chad Nusbaum and his colleagues present the sequence of this chromosome and a new analysis. They conducted a genome-wide comparison of human and other mammalian DNA, and found similarities in the levels of non-protein-coding regions among mammals. According to their work, the prevalence of these regions is uncorrelated with gene density. The study suggests that there is more to non-coding DNA than meets the eye, especially when it seems to be evolutionarily conserved across a number of mammalian genomes. CONTACT Chad Nusbaum (Broad Institute of MIT and Harvard, Cambridge, MA, USA)
E-mail: chad@broad.mit.edu (C) Nature press release.
Message posted by: Trevor M. D'Souza
|
|
Variants Associated with Pediatric Allergic Disorder
Mutations in PHF6 Found in T-Cell Leukemia
Genetic Risk Variant for Urinary Bladder Cancer
Antibody Has Therapeutic Effect on Mice with ALS
Regulating P53 Activity in Cancer Cells
Anti-RNA Therapy Counters Breast Cancer Spread
Mitochondrial DNA Diversity
The Power of RNA Sequencing
‘Pro-Ageing' Therapy for Cancer?
Niche Genetics Influence Leukaemia
Molecular Biology: Clinical Promise for RNA Interference
Chemoprevention Cocktail for Colon Cancer
more news ...
|