home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Evidence that the Way Germline Stem Cells Divide is Influenced by Support Cells

  October, 12 2000 2:58
your information resource in human molecular genetics

Crucial for realizing the therapeutic potential of stem cells is a better understanding of their behaviour. This week (Nature, Vol. 407, No. 6805, 12 Oct 2000), two papers on male fruit-fly (Drosophila) germline cells (those that give rise to sperm) further that understanding with evidence that the way germline stem cells divide is influenced by the support cells that surround them.

Margaret T. Fuller of Stanford University School of Medicine, California and colleagues and Stephen DiNardo and colleagues of the University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, find that support cells control germline stem cell numbers by ensuring that these stem cells divide 'asymmetrically'.

Stem cells have the potential to produce the variety of highly specialized ('differentiated') cells needed by the body - such as eggs, sperm, blood, skin or liver. Stem cells can either renew themselves by dividing 'symmetrically' to create two daughter stem cells, or they can divide asymmetrically to produce one stem cell daughter and one differentiated daughter cell.


Margaret T. Fuller
tel +1 650 725 7681
fax +1 650 725 7739
e-mail fuller@cmgm.stanford.edu

Stephen DiNardo
tel +1 215 898 1367
fax +1 215 898 9871
e-mail sdinardo@mail.med.upenn.edu

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.