home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Sex Chromosome Genes Directly Affect Brain Sexual Differentiation

 
  September, 20 2002 8:58
your information resource in human molecular genetics
 
     
Differences in gonadal secretions cause sex differences in the brain; the male brain develops differently than the female brain because of higher levels of testosterone during fetal and neonatal life. Using mice in which the genetic sex of the brain (XX versus XY) was independent of gonadal phenotype (testes versus ovaries), it was found (Nature Neuroscience) that XY and XX brain cells differed in phenotype, indicating that a brain cell’s complement of sex chromosomes may contribute to its sexual differentiation. The ‘in vitro’ system described offers significant advantages for unraveling the cellular and molecular mechanisms of sex-chromosome gene action.

Author Contact:

Arthur P. Arnold
Dept. Physiol. Sci. and Lab. Of Neuroendocrinology
Brain Research Institute
University of California
Los Angeles, CA 90095
USA
E-mail: arnold@ucla.edu

Abstract available online.

(C) Nature Neuroscience press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.