A Commentary published in European Journal of Human Genetics (Vol. 14, pp. 978-980, 2006) by Ian J Jackson, MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
The genetic basis of variation in skin pigmentation between people of African, Asian and European origins has only recently come under study, and is far from being fully understood. Recent work indicates that variation in a gene of the solute channel family, SLC24A5, may be one of the major causes of skin colour differences between European and non-European populations. The conservation of linked variants around the locus in Europeans indicates that this variant swept rapidly, under selection, though the population.
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Dr. I. J. Jackson, E-mail: Ian.Jackson@hgu.mrc.ac.uk
(C) European Journal of Human Genetics.
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