Good news! An ingredient found in red wine can extend lifespan by up to 70% - if you're yeast, that is.
It's well known that caloric restriction - eating fewer calories - can extend lifespan across a range of species, but most of us would prefer to have our cake, eat it and still live longer. In a report published online by Nature this week, David A. Sinclair and colleagues report several drug-like molecules that can achieve this in the baker's yeast Saccharomyces cerevisiae. These plant polyphenols work by activating common enzymes, such as Sir2 in yeast or SIRT1 in humans, which have been linked to calorically restricted life extension in creatures such as nematode worms. One molecule, resveratrol, is abundant in red wine and has previously been found to exert a protective effect against cancer, atherosclerosis and other age-related diseases.
A word of warning - before one can endorse a strict Rioja regimen, the safety and effectiveness of the compounds need to be evaluated rigorously in higher organisms such as laboratory mice.
via the Public Information Office
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(C) Nature press release.
Message posted by: Trevor M. D'Souza