There is a huge amount of genome-wide expression data available in public repositories (such as NCBI GEO and ArrayExpress) that can be explored to complement or enhance novel biological findings. A recent paper published in Nucleic Acids Research describes a new web server (Microarray retriever) that allows a search of available datasets in both public repositories and to retrieve the respective primary data in an automatic and organized fashion. It is possible to enter different types search terms as input (such as PMIDs, accession numbers or keywords) and there are options to select specific organisms, platforms or repositories.
Microarray retriever will be helpful, in addition to other available web servers, for researchers working in genomics and exploring the molecular basis of many medical and biological problems.
Author: Peter A. C. 't Hoen
Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
Ivliev AE, 't Hoen PA, Villerius MP, den Dunnen JT, Brandt BW. Microarray retriever: a web-based tool for searching and large scale retrieval of public microarray data. Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W327-31. Paper available online.
The PGA program is available at MaRe website
Message posted by: Diego Forero