home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Human Chromosome 7 Decoded

 
  July, 14 2003 8:10
your information resource in human molecular genetics
 
     
The sequence and analysis of human chromosome 7 is revealed in this week's Nature (Vol. 424, No. 6945, dated 10 July 2003, pp. 157-164). The structure, deciphered by Richard K. Wilson and colleagues, is the largest of our 24 chromosomes to have been unravelled so far.

Chromosome 7 has been linked to many intensively studied human diseases including cystic fibrosis, hereditary deafness and cancer. The new sequence data, which is over 99% complete, show extremely good concordance with previous physical and genetic maps. The chromosome is now known to contain 153 million base pairs and 1,150 protein-coding genes.

Unusually large amounts of the chromosome sequence are duplicated, the team found. The repetitions may play a role in helping new genes to evolve, and may also be associated with disease. Duplicated segments were found in a region of the chromosome known to be associated with Williams–Beuren syndrome, a congenital condition causing a characteristic elfin-like face, mental retardation, growth deficiency and cardiovascular anomalies.

The chromosome 7 sequence data, from the Human Genome Project, have been deposited in publicly accessible worldwide genome databases from the beginning of the project. Together, this information should help researchers to understand the genetic basis for human health and disease.

CONTACT:

Richard Wilson
(Washington University School of Medicine, St. Louis, MO, USA)
Tel: +1 314 286 1804
E-mail: rwilson@watson.wustl.edu

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.