The discovery of a gene that is overactive in an aggressive type of brain tumor may lead to better understanding of how such cancer spreads and help doctors predict how quickly tumors are likely to recur after treatment, according to a new report.
Researchers at Cedars-Sinai Medical Center in Los Angeles, California have found that a gene known as laminin-8 is overexpressed in a type of brain tumor called glioblastoma multiforme (GBM), a quickly spreading form of brain cancer that is notoriously resistant to treatment. The team speculates that the overexpression of laminin-8 may be a critical step in the process by which less-advanced brain tumors progress to GBMs.
Dr. Julia Y. Ljubimova and her colleagues report the findings in the July 15th issue of the journal Cancer Research.
Full Press release in the Reuters, July 16, 2001.
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