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Side effects of drugs determined by genetic variability

  July, 4 2001 2:38
your information resource in human molecular genetics
Genetic variability may predict severity of side effects from methotrexate, a common chemotherapy drug

Nearly half of all Americans carry a genetic mutation that interferes with their ability to metabolize folate. Such people, when exposed to a poor diet or certain drugs, can suffer significant clinical consequences, particularly if they are among the approximately 10 percent of Americans born ith the most limited abilty to process this nutrient.

NIH/National Cancer Institute

Kristen Woodward
Fred Hutchinson Cancer Research Center

Message posted by: Wouter Kalle

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