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Side effects of drugs determined by genetic variability

 
  July, 4 2001 2:38
your information resource in human molecular genetics
 
     
Genetic variability may predict severity of side effects from methotrexate, a common chemotherapy drug

Nearly half of all Americans carry a genetic mutation that interferes with their ability to metabolize folate. Such people, when exposed to a poor diet or certain drugs, can suffer significant clinical consequences, particularly if they are among the approximately 10 percent of Americans born ith the most limited abilty to process this nutrient.

NIH/National Cancer Institute

Contact:
Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center


Message posted by: Wouter Kalle

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