home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Antibodies May Hold the Secret of Unravelling the Mystery of Sjogren's Syndrome

  July, 20 2000 4:21
your information resource in human molecular genetics
A recent study by Adelaide medical researchers has identified a possible link between the symptoms of Sjogren's syndrome and an antibody in the blood which interferes with nerve transmission.

Dr Maureen Rischmueller, consultant rheumatologist in the Department of Rheumatology at The Queen Elizabeth Hospital said, "Sjogren's syndrome is a common auto immune rheumatic disease affecting up to one percent of the population, predominantly women. "It is typified by severe dryness of the eyes and mouth with accelerated dental caries, often in association with fatigue, muscle and joint pains, swollen glands and other widespread complaints."

Results of the study published this week in the international journal Arthritis and Rheumatism (Vol. 43, No. 7., pp. 1647-1654), demonstrate for the first time that antibodies found in the bloodstream of patients with primary Sjogren's syndrome which bind to the receptors of small nerve endings found in glandular structures and other organs have the effect of blocking transmission through these nerves.

Dr Rischmueller and associates Dr Sally Waterman and Professor Tom Gordon, Department of Immunology, Allergy and Arthritis, FMC hope to obtain major funding to continue their work into this debilitating illness, the results of which will also aid in the understanding and treatment of other autoimmune diseases.

The current study was carried out in collaboration with the North Western Adelaide Health Service, Adelaide University and the Flinders Medical Centre.

Contact: Jan Rohrsheim
Adelaide University

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2018 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.