home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Potential Drug to Prevent Atherosclerosis Identified

 
  July, 14 2000 6:57
your information resource in human molecular genetics
 
     
STOP THE CLOT

Hiroshi Okamoto of the Central Pharmaceutical Research Institute, JT Inc, Takasuki, Osaka, Japan, and colleagues have identified what could be a potent drug to prevent atherosclerosis. As they explain in this week's Nature (Vol. 406, Issue 6792, July 13, 2000), the compound, catchily named 'JTT-705', inhibits the protein 'CEPT'. The role of CEPT has been hitherto unclear, but the researchers show that, by influencing the lipid make-up of blood, it may contribute to the narrowing and hardening of blood vessels that constitutes atherosclerosis.

In cholesterol-fed rabbits, they report that JTT-705 brings about beneficial changes in blood HDL-C and LDL-C - sometimes called 'good cholesterol' and 'bad cholesterol', respectively - that "may be reasonably extrapolated to predict the changes in plasma lipids in humans treated with this drug," Okamoto's group speculates.

CONTACT:

Hiroshi Okamoto tel +81 726 81 9700, fax +81 726 81 9722,
e-mail ye6h-okmt@asahi-net.or.jp

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.