home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Smog Stresses the Skin

 
  June, 19 2009 8:55
your information resource in human molecular genetics
 
     
Ozone may have damaging effects on a skin enzyme that helps break down environmental pollutants. Using cells grown in culture, researchers report these findings online in Journal of Investigative Dermatology.

Ozone is a main component of photochemical smog. When sun rays hit chemical compounds emitted into the atmosphere from cars, factories and other man-made sources, photochemical smog is created. Since smog is a volatile compound, it can break down into free radicals which in turn are damaging to organic molecules. This can lead to various short and long-term health effects.

Hasan Mukhtar and colleagues studied smog's toxic effects on normal human skin cells grown in the lab. They focused on one component of photochemical smog in particular - ozone. The scientists found that when normal skin cells were exposed to ozone there was an increased likelihood for cell damage. This cell damage increased the expression of the Cytochrome P450 enzymes - cellular proteins crucial in the metabolism of many chemicals - in skin cells, which strongly suggests that there are toxicological consequences of ozone exposure.

Several large cities, such as Los Angeles, Beijing, and Mexico City are known to have extended periods of smog that can build up to dangerous levels. Further research is required to confirm these findings in people.

Author contact:

Hasan Mukhtar (University of Wisconsin, Madison, WI, USA)
E-mail: hmukhtar@wisc.edu

Editorial contact:

Joyce-Rachel John (Senior Publishing Manager, Journal of Investigative Dermatology, New York, NY, USA)
E-mail: j.john@natureny.com

Abstract available online.

(C) Journal of Investigative Dermatology press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.