home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Combination Vaccine Delivers Double Blow

 
  June, 2 2003 5:00
your information resource in human molecular genetics
 
     
A new vaccine approach that delivers a one-two punch could give the immune system an edge against malaria, AIDS and other exigent diseases in people, Adrian Hill and colleagues report in the June issue of Nature Medicine.

The researchers tested their method using a malaria vaccine in human volunteers. They first treated the volunteers with the parasite’s DNA, followed by a boost with a modified poxvirus that expresses parasite proteins. The ‘prime’ and ‘boost’ contained distinctly different proteins from the parasite.

Neither DNA nor poxvirus in isolation induced a potent response, the team found. But the combination ramped up the activation of T cells -- a subset of immune cells -- and provided partial protection against malaria infection. The approach has the potential to outshine more conventional experimental vaccines against malaria. Similar vaccine approaches have already shown promise in AIDS vaccine trials.

Author contact:

Adrian Hill
Nuffield Department of Medicine
University of Oxford, UK
Tel: +44 1865 222301
E-mail: adrian.hill@imm.ox.ac.uk

Also available online.

(C) Nature Medicine press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.