home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Life Without Dad

 
  May, 2 2007 21:35
your information resource in human molecular genetics
 
     
Genomic imprinting is not always essential for seed development, a study published online in Nature suggests. The finding may have implications for stem cell research.

Genomic imprinting is a form of gene regulation that starts early in life. It causes certain genes to be expressed from just the maternally inherited DNA, whilst others are expressed only from the paternal DNA. The phenomenon is well known in mammals, but it also occurs in flowering plants.

In a fertilized seed the endosperm provides nutrients to the developing embryo. Arp Schnittger and colleagues created a mutant plant in which the endosperm is derived solely from maternal DNA. They find that, in a certain mutant background that affects chromatin remodelling, the endosperm can develop normally without a paternal contribution, suggesting that genomic imprinting per se is not essential for seed development. Mammalian embryos lacking appropriate imprints die, but the uniparental endosperm seedlings in this study are viable albeit smaller than normal.

Imprinting is a hot topic in stem cell research, because researchers are trying to clone viable, healthy embryos from cells lacking imprints. So the study contributes useful information to this field and also says something about the evolution of endosperm.

Author contact:

Arp Schnittger (University of Cologne, Germany)
E-mail: schnitt@mpiz-koeln.mpg.de

Abstract available online.

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.