A strategy for designing more effective cholesterol-lowering drugs may come from the first studies of the structural mechanism by which the widely prescribed statin drugs, such as Lipitor and Zocor, lower cholesterol. Although the statin drugs -- which are regarded as blockbuster drugs for the pharmaceutical industry -- are effective at reducing cholesterol, the new structural studies suggest there is room for improvement.
Research published in the May 11, 2001, issue of the journal Science. For the full story go to http://www.hhmi.org/news/deisenhofer.html
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