home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Gene Linked To Tuberculosis Susceptibility

 
  April, 19 2005 9:59
your information resource in human molecular genetics
 
     
Each year tuberculosis (TB) infects about eight million people, killing an estimated two million of these. Factors such as stress and malnutrition can influence susceptibility to the disease, but scientists have also longed to understand how genes can influence whether an individual develops TB after infection.

Igor Kramnik and his colleagues now add a new piece to this genetic puzzle. In a letter in the 07 April 2005 issue of Nature (Vol. 434, No. 7034, pp. 767-772), they show that the Ipr1 gene in the sst1 region of mouse chromosome 1 can determine susceptibility to TB. The authors suggest that SP110, the human homologue of this gene, might be a candidate a candidate link to TB susceptibility in people.

"These studies not only provide insight into a novel aspect of TB pathogenesis, but, if validated in humans, may reveal new targets for drug treatments," write Nada Jabado and Philippe Gros in an accompanying News and Views article.

CONTACT

Igor Kramnik (Harvard School of Public Health, Boston, MA, USA)
E-mail: ikramnik@hsph.harvard.edu

Philippe Gros (McGill University, Montreal, Canada)
E-mail: philippe.gros@mcgill.ca

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.