home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

SARS Vaccine Yields Promising Results In Mice

  April, 13 2004 8:37
your information resource in human molecular genetics
An experimental vaccine against the SARS coronavirus has yielded promising results in mice. The gene-based technique is described in 01 April 2004 issue of Nature (Vol. 428, No. 6982, pp. 561-564).

Gary J. Nabel and colleagues have made a DNA vaccine that codes for a surface protein of the SARS coronavirus. Treatment with the vaccine stimulates an antibody response and induces protective immunity to the SARS virus in mice. Viral replication also drops by over 6 orders of magnitude in the lungs of vaccinated rodents.

DNA vaccines are a relatively new idea. They are known to induce immunity in animal models of influenza, HIV, Ebola and other viruses, but have only recently begun to be tested in humans. The new therapy points to gene-based vaccination as a possible way of protecting against SARS, but the limitations of the animal models of the disease mean that a lot needs to be done before a human vaccine becomes practicable.


Gary J. Nabel
Vaccine Research Center
Bethesda, MD
Tel: +1 301 496 1852
E-mail: gnabel@nih.gov

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2018 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.