home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Test Reveals Obesity Subtypes

 
  March, 24 2003 10:32
your information resource in human molecular genetics
 
     
A report in this week's Nature (Vol. 422, No. 6929, 20 March 2003, pp. 297-302) suggests that obesity may not be one disease, but a collection of conditions, each with its own genetic identity. This discovery may lead to the development of tailor-made medicines aimed at subtypes of diseases such as obesity, diabetes and osteoporosis. Eric E. Schadt of Rosetta Inpharmatics, Kirkland, Washington, and colleagues combined clinical information about obesity, data from DNA microarrays and whole-genome sequences to compare and contrast the make-up of genetically obese mice. They found that overweight mice can be subdivided into two groups on the basis of their genes. They also found a 'hotspot' of obesity-related genes on chromosome 2. This combined approach may help researchers to identify disease-related genes that could otherwise be missed. The researchers have also successfully applied their technique to maize and humans, creating a database that may help identify new groups of genes related to complex plant and human characteristics.

"The combination of genetic information and gene expression is expected to significantly advance the fulfillment of the long-awaited promises of genomics to improve healthcare," says Ariel Darvasi of the Hebrew University of Jerusalem, Israel, in an accompanying News and Views article.

Contact:
Eric E. Schadt
Tel: +1 425 823 7368
E-mail: eric_schadt@merck.com

Dr. Ariel Darvasi
Tel: +972 2 6584303
E-mail: arield@cc.huji.ac.il

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.