Postnatal stem cells need the MII1 gene switched on if they are to form neurons, a Nature paper reveals. Understanding the mechanisms that guide stem cells to become one cell type or another is important if the cells are to be used therapeutically.
Gene expression is regulated, at least in part, by the structure of chromatin ? the complex of nucleotides and protein that make up chromosomes. It's known that MII1 influences chromatin structure, and Arturo Alvarez-Buylla and colleagues now show that MII1 is essential for neural stem cells to form neurons, but not the supportive, non-neuronal glial cells found in the postnatal brain.
Arturo Alvarez-Buylla (University of California, San Francisco, CA, USA)
Abstract available online.
(C) Nature press release.
Message posted by: Trevor M. D'Souza
Bookmark and Share this page (what is this?)
Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.
Use the links below to share this article on the social bookmarking site of your choice.
Read more about social bookmarking at Wikipedia - Social Bookmarking