home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

RNA Interference Humbles Hepatitis

 
  February, 17 2003 8:45
your information resource in human molecular genetics
 
     
RNA interference (RNAi) is a powerful technique for silencing the expression of genes and has been described as the most important scientific advance in recent years. But its potential to treat or prevent disease in live animals has thus far been unproven.

In the March issue of Nature Medicine, Judy Lieberman and her colleagues report for the first time that RNAi can successfully prevent liver injury and death in a mouse model of hepatitis.

The researchers used RNAi to silence Fas, which is implicated in a wide array of liver diseases, including autoimmune, viral and transplant rejection hepatitis. Intravenously injecting inhibitory RNAs against Fas, without the need for a delivery vector or virus, allowed mice to survive in two models of autoimmune hepatitis, the researchers report.

Author contact:
Judy Lieberman
Center for Blood Research
Harvard Medical School
Boston, MA
USA
Tel: +1 617 278 3381
E-mail: lieberman@cbr.med.harvard.edu

Also available online.

(C) Nature Medicine press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2016 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.