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Gene Could Predispose People To Adult-Onset Or ‘Type II’ Diabetes

  January, 5 2001 4:29
your information resource in human molecular genetics

Researchers have identified a gene that could predispose people to adult-onset or ‘type II’ diabetes (Nature, Vol. 409, No. 6816, 04 Jan 2001). The gene, SHIP2, is also a potential therapeutic target for the treatment of this non-insulin-dependent type of diabetes, which is on the increase in the developing world.

Stephane Schurmans of IRIBHN, Gosselies, Belgium, and colleagues have engineered mice lacking SHIP2; these mice show that the gene is a critical and essential down-regulator of insulin signalling and insulin sensitivity.


Stephane Schurmans
tel +32 2 650 98 21
fax +32 2 650 98 20
e-mail sschurma@ulb.ac.be

(C) Nature press release.

Message posted by: Trevor M. D'Souza

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