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Keystone Symposia, Breckenridge, Colorado
September 18 - 23, 2007
In recent years, knowledge of TRP channel biology has increased at a tremendous pace. These channels are now known to be regulated in two general ways: by physical perturbations (i.e., temperature, mechanical) or by classical signal transduction cascades (most commonly phospholipases). In addition, mutations in TRP channels are known to be the basis for a number of inherited diseases, including mucolipidosis and polycystic kidney disease. However, there is a great deal of controversy regarding the mechanisms of activation and regulation of many TRPs, especially those thought to be involved in the long elusive mechanism of store-operated channels. This symposium will highlight current knowledge of structure, function, regulation and pharmacology of the TRPs, especially with regard to current controversies. Additionally, the roles of TRPs in diseases will be addressed, including the potential for treating diseases through knowledge of their regulation, and through design of therapeutic agents to modify their behavior.
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Organized by:
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James W. Putney, Bernd Nilius and Craig Montell |
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Invited Speakers:
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- Indu Ambudkar, NIDCR, National Institutes of Health
- Rene Bindels, Radboud University Nijmegen Medical Centre
- Lutz Birnbaumer, NIEHS, National Institutes of Health
- Victoria Bolotina, Boston Medical Center
- Michael Caterina, Johns Hopkins School of Medicine
- Andrea Fleig, University of Hawaii
- Veit Flockerzi, University of Saarland
- Don Gill, University of Maryland School of Medicine
- Owen Hamill, University of Texas Medical Branch
- Su Li, Novartis Institutes for BioMedical Research
- Emily Liman, University of Southern California
- Craig Montell, Johns Hopkins University
- Yasuo Mori, Kyoto University
- Shmuel Muallem, University of Texas Southwestern Medical Center
- Bernd Nilius, Katholieke Universiteit Leuven
- Martha Nowycky, UMDNJ-New Jersey Medical School
- Ardem Patapoutian, The Scripps Research Institute
- Mu-ming Poo, University of California, Berkeley
- James Putney, NIEHS, National Institutes of Health
- Stefan Somlo, Yale School of Medicine
- X.Z. Xu, University of Michigan
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Deadline for Abstracts:
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May 18, 2007
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Registration:
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Please see website
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E-mail:
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info@keystonesymposia.org
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