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Keystone Symposia, Breckenridge, Colorado
April 11 - 16, 2007
Epigenetic regulatory mechanisms provide cells with transcriptional memory, allowing cells to stably maintain expression patterns for many divisions, and developmental flexibility, facilitating programmed alterations in gene expression during embryogenesis. Recent developments indicate that surprisingly dynamic modifications in chromatin structure are employed to regulate gene expression and have far-reaching consequences for cell fate decisions and normal and pathological development. Significant progress has been made in understanding the role of epigenetics in topics as diverse as cloning, cancer biology, genomic imprinting, development in plants and animals, and DNA repair. Similar molecules are employed by different organisms to affect chromatin structure and achieve epigenetic regulation. However the molecular mechanisms by which the changes in chromatin structure modulate gene expression remain mysterious. This Keystone Symposium on ‘Chromatin Structure in Development and Disease’ will bring together diverse fields, from basic studies in model organisms to medical research to biotechnology. The primary aim of the meeting will be to promote communication between diverse groups of epigenetic and chromatin researchers, facilitating cross dissemination of approaches to understanding these fascinating and medically important processes.
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Organized by:
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Barbara Panning and Hiten D. Madhani |
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Invited Speakers:
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- Geneviève Almouzni, Centre National de la Recherche Scientifique
- Marisa Bartolomei, University of Pennsylvania School of Medicine
- Timothy Bestor, Columbia University College of Physicians and Surgeons
- Sarah Elgin, Washington University
- Daniel Gottschling, Fred Hutchinson Cancer Research Center
- Steven Henikoff, Fred Hutchinson Cancer Research Center
- Douglas Higgs, Molecular Medicine Oxford
- Steven Jacobsen, HHMI/University of California-Los Angeles
- Rudolf Jaenisch, Whitehead Institute for Biomedical Research
- Robert Kingston, Massachusetts General Hospital
- Nevan Krogan, University of California, San Francisco
- Jeannie Lee, Massachusetts General Hospital
- Hiten Madhani, University of California, San Francisco
- Danesh Moazed, Harvard Medical School
- Barbara Panning, University of California, San Francisco
- Ralph Scully, Beth Israel Deaconess Medical Center
- Yang Shi, Harvard Medical School
- Maarten Van Lohuizen, Netherlands Cancer Institute
- Richard Young, Whitehead Institute for Biomedical Research
- Yi Zhang, University of North Carolina at Chapel Hill
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Deadline for Abstracts:
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Dec. 11, 2006
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Registration:
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Please see website
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E-mail:
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info@keystonesymposia.org
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