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Keystone Symposia, Vancouver, British Columbia, Canada
February 1 - 6, 2007
Although immune regulation by T suppressor cells was first proposed more than 30 years ago, recent studies in both man and experimental animals now provide a solid basis for the role of T cells in immune regulation. It is now widely accepted that the major T effector functions are mediated by two distinct subpopulations of T cells -- Th1 and Th2 -- cells which produce distinct cytokine profiles. In addition, both naturally occurring and adaptive T suppressor/regulatory T cells have been shown to play major roles in the control of all immune responses. This meeting will review the molecular basis for the differentiation of Th1/Th2 cells from naive precursors. The second goal is to present the most up to date information on the development, function, mechanism of action, and homeostasis of regulatory T cells. Modulation of both Th1/Th2 differentiation and regulatory T cell function are about to be translated to the clinic. Several presentations will address the approaches used and the results of preclincal and clinical trials involving manipulation of regulatory T cell function.
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Organized by:
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Ethan M. Shevach, Fiona M. Powrie and Alexander Y. Rudensky |
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Invited Speakers:
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- Yasmine Belkaid, National Institutes of Health
- Albert Bendelac, University of Chicago
- Christophe Benoist, Joslin Diabetes Center
- Bruce Blazar, University of Minnesota
- Jeffrey Bluestone, University of California, San Francisco
- Lucienne Chatenoud, Hopital Necker
- Richard Flavell, Yale University School of Medicine
- Alf Hamann, Charité University Medicine Berlin
- Kim Hasenkrug, NIAID, National Institutes of Health
- Adrian Hayday, King's College London School of Medicine
- Juan Lafaille, New York University School of Medicine
- Ruslan Medzhitov, Yale University School of Medicine
- Kingston Mills, Trinity College, Dublin
- Drew Pardoll, Johns Hopkins School of Medicine
- Fiona Powrie, University of Oxford
- Anjana Rao, Harvard Medical School
- Maria Roncarolo, San Raffaele Telethon Institute for Gene Therapy
- Alexander Rudensky, University of Washington School of Medicine
- Shimon Sakaguchi, Institute for Frontier Medical Sciences, Kyoto University
- Ethan Shevach, NIAID, National Institutes of Health
- Haruhiko Suzuki, Nagoya University School of Medicine
- Dale Umetsu, Children's Hospital Boston
- Derya Unutmaz, Vanderbilt University Medical Center
- Harald von Boehmer, Harvard Medical School
- Herman Waldmann, University of Oxford
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Deadline for Abstracts:
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Oct. 2, 2006
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Registration:
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Please see website
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E-mail:
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info@keystonesymposia.org
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