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MicroRNAs and siRNAs: Biological Functions and Mechanisms

 
  June 15, 2006  
     
 


Keystone Symposia, Keystone, Colorado
January 28 - February 2, 2007


MicroRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs) act as guide RNAs to direct gene-silencing pathways in eukaryotes. These silencing pathways require related core components to process and utilize the guide RNAs. Nonetheless, they have evolved to perform different biochemical functions, mediating either transcriptional or posttranscriptional silencing important for numerous endogenous gene-regulatory programs as well as viral resistance, transposon suppression, centromere function, and programmed genome rearrangement. The aim of this meeting is to report on recent advances in understanding both the molecular mechanisms of siRNA- and miRNA-directed silencing and the biological functions of these mechanisms.
 
 
Organized by: David P. Bartel and Shiv I.S. Grewal
Invited Speakers: - Robin Allshire, University of Edinburgh
- Victor Ambros, Dartmouth Medical School
- David Barford, Institute of Cancer Research
- David Bartel, Massachusetts Institute of Technology
- David Baulcombe, Sainsbury Laboratory
- James Carrington, Oregon State University
- Xuemei Chen, University of California, Riverside
- Carlo Croce, Ohio State University College of Medicine
- Sarah Elgin, Washington University
- Witold Filipowicz, Friedrich Miescher Institute for Biomedical Research
- Martin Gorovsky, University of Rochester
- Shiv Grewal, National Institutes of Health
- Gregory Hannon, Cold Spring Harbor Laboratory
- Steven Jacobsen, HHMI/University of California-Los Angeles
- Leemor Joshua-Tor, Cold Spring Harbor Laboratory
- V. Kim, Seoul National University
- Anna Krichevsky, Brigham and Women's Hospital, Harvard Medical School
- Marjori Matzke, Gregor Mendel Institute of Molecular Plant Biology
- Craig Mello, HHMI and University of Massachusetts Medical School
- Dinshaw Patel, Memorial Sloan-Kettering Cancer Center
- Ronald Plasterk, Hubrecht Laboratory
- Phillip Sharp, Massachusetts Institute of Technology
- Ramin Shiekhattar, Wistar Institute
- Erik Sontheimer, Northwestern University
- Thomas Tuschl, Rockefeller University
- Phillip Zamore, University of Massachusetts Medical School
 
Deadline for Abstracts: Sept. 28, 2006
 
Registration: Please see website
E-mail: info@keystonesymposia.org
 
   
 
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