HUM-MOLGEN events: Cambridge Healthtech Institute's Advancing Library Design and Organic Synthesis

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Cambridge Healthtech Institute's Advancing Library Design and Organic Synthesis

January 28, 2003

Cambridge Healthtech Institute, Hilton La Jolla Torrey Pines, 10950 N. Torrey Pines Rd., La Jolla, CA 92037
February 24-27, 2003

Frustration with the lack of drugs entering the market has forced the pharmaceutical industry to examine how libraries are designed and synthesized. Emphasis has shifted from making large combinatorial libraries to smaller, more target-focused libraries, filtered to exclude non-drug or non-leadlike entities. This has been facilitated largely by increased knowledge of biological target structure, in conjunction with advances in computational tools. Combichem techniques are now being used more frequently in medchem projects and yielding results in lead discovery and optimization. Efforts to produce diverse natural product-like libraries in the hope of finding compounds that will be more effective in the clinic are also gaining a great deal of attention. Compound storage and stability are critical issues for many organizations that handle large compound collections. All of these topics will be discussed at length during this event. This conference will include a one-day special event showcasing results from microwave-assisted synthesis in organic, medicinal, and combinatorial chemistry. Presentations will be given by key industrial and renowned academic players in this new exciting field.

Organized by:

Cambridge Healthtech Institute

Invited Speakers:

Dr. K. Barry Sharpless,
The Scripps Research Institute
Dr. Alan R. Katritzky,
University of Florida
Advisory Committee

Sponsoring Publications:
Current Drug Discovery
Drug Discovery and Development
Elsevier Science
Genome Research
Kluwer
PharmaGenomics
Physiological Genomics
Wiley-VCH

Web Partners:
Combichem.net
HTScreening.net
Processdevelopment.net

Dr. Prabhat Arya, National Research Council of Canada
Prof. Hicham Fenniri, Purdue University
Dr. Adam Golebiowski, Procter & Gamble Pharmaceuticals
Dr. Timothy Herpin, Bristol-Myers Squibb Company
Dr. C. Oliver Kappe, Karl-Franzens-University Graz
Dr. Christopher A. Lipinski, Pfizer Global Research and Development
Dr. Aubrey J. Mendonca, Polymer Laboratories Inc.
Dr. David Portlock, Procter & Gamble Pharmaceuticals
Prof. Herbert Waldmann, Max-Planck-Institut für Molekulare Physiologie