HUM-MOLGEN events: Linking Genomic Information with Drug Design

HUM-MOLGEN -> Events -> Meetings and Conferences

Linking Genomic Information with Drug Design

August 03, 2001

American Chemical Society, Chicago, Illinois
Aug. 27, 2001-Aug. 29, 2001

Symposium schedule
Monday Morning, August 27, 2001
9:00 — 43. Use of genomic information in drug design. Paul Caron, Vertex Pharmaceuticals
9:30 — 44. Comparative protein structure modeling of genes and genomes. Andrej Sali, Rockefeller University
10:00 — 45. Homology models, high throughput docking, and drug design David J. Diller, Pharmacopeia
10:30 — Intermission.
10:45 — 46. New modeling developments at Merck. Simon Kearsley, Merck, Sharpe, Dohme
11:15 — 47. Fingerprint analysis of proteins and ligands for high-throughput screening. W. Todd Wipke, Z. Yang, M. Evans, J. P. Hall, University of California, Santa Cruz
11:45 — 48. Iterative design of gene-family directed screening libraries. Michelle L. Lamb, E. K. Bradley, D. C. Spellmeyer, M. J. Suto, P. D. J. Grootenhuis, Dupont Pharmaceuticals.

Monday Afternoon, August 27, 2001
1:15 — 59. Target class approaches to genome mining and drug design. Jonathan S. Mason, S. R. Krystek, D. F. Sitkoff, Bristol Myers Squibb
1:45 — 60. The serine protease family as a model system for rapid gene discovery and target identification for the development of novel anticancer drugs. Ed Madison, Corvas International.
2:15 — 61. Targeting a shared essential protein interaction interface in nuclear hormone receptor signaling pathways. R. Kip Guy, T. R. Geistlinger, J. M. R. Moore, J. R. Arnold, T. A. Robertson, I. D. Kuntz ,University of California, San Francisco
2:45 — Intermission.
3:00 — 62. High-throughput mapping and analysis of protein functional epitopes. D. Rick Artis, S. S. Sidhu, Genentech
3:30 — 63. Chemical approaches for functional proteomic profiling. D. Greenbaum, A. Baruch, L. Hayrapethian, Z. Bozdech, J. DeRisi, Matt Bogyo, University of California, San Francisco
4:00 — 64. Bringing drug discovery to the genome. Michael Millburn Structural GenomiX
4:30 — 65. Which sequence should I target? The advantages of an integrated platform in structural proteomics Jaque S. Fetrow, GenFormatics

Tuesday Morning, August 28, 2001
9:00 — 83. Chemical library approaches for proteomics. Brad Backes, Novartis Institute for Functional Genomics
9:30 — 84. Structural characterization of an estrogen receptor _ agonist/estrogen receptor _ antagonist reveals a novel mode of receptor antagonism. Andy
K. Shiau, D. Barstad, J. T. Radek, M. J. Meyers, B. S. Katzenellenbogen, D. A. Agard, G. L. Greene, Tularik
10:00 — 85. Docking and scoring inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1). R. A. Kumpf Agouron Pharmaceuticals/ Pfizer Global Research
10:30 — Intermission.
10:45 — 86. Rapid docking to protein families. Ken Foreman, D. Joseph-McCarthy, J. C. Alvarez, Wyeth-Ayerst/Genomics Institute
11:15 — 87. ASITE: A fast general algorithm for automatically finding protein active sites. W. T. Wipke, M. Evans, B. Kislin, R. McClellan, University of California, Santa Cruz

Wednesday Morning, August 29, 2001
9:00 — 169. Recognition of NAD by enzymes: Molecular dynamics simulations, database mining, and high resolution protein crystallography, J. J. Tanner, P. E. Smith, C. A. Bottoms, University of Missouri
9:30 — 170. A new Linear Response Method based on Continuum Solvent model for ligand-receptor binding affinity prediction. R. Zhou, R. A. Friesner, R. C. Rizzo, W. L. Jorgensen, IBM Research
10:00 — Intermission.
10:15 — 171. Fold recognition using composite structural templates followed by constrained global minimization. Y. An, D. Standley, D. Pincus, V. Eyrich, R. A. Friesner Columbia University
10:45 — 172. Aligning genomic sequences to functionally important surface pockets on protein structures for drug discovery. Y. Turpaz, J. Liang, University of Illinois

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Organized by:

Jim Arnold

Invited Speakers:

Rick Artis, Ph.D.
Ed Madison, Ph.D.
Stephen Burley, Ph.D.
Jonathan Mason, Ph.D
Jaque Fetrow, Ph.D.
Michael Milburn, Ph.D.
R. Kip Guy, Ph.D.
Andrej Sali, Ph.D.

Deadline for Abstracts:

April 2001

Registration:

REGISTRATION INFORMATION

Late Registration: Attendees who register online between July 28th and August 17th will pay the on-site registration fee, but will not have to stand in line to register, and can simply pick up credentials at the "pre-registration" counters on-site. Please note this late registration option is available only via the Web. Fax and mailed registrations forms will not be accepted after July 27th.

Late Registrants may proceed to the "Pre-registration" counters at McCormick Place to pick up credentials (please bring confirmation letter) during the hours listed below:

On-site Registration: Attendees my also register on site at McCormick Place. This year as an added service, ACS will provide self-registration counters along with the traditional "attended" registration counters. On-site registration fees apply.

On-Site Registration Hours at McCormick Place are as follows:

Saturday, August 25
3:00 PM to 7:00 PM

Sunday, August 26
7:30 AM to 7:00 PM

Monday, August 27
7:30 AM to 5:00 PM

Tuesday, August 28
7:30 AM to 5:00 PM

Wednesday, August 29
7:30 AM to 4:00 PM

Thursday, August 30
7:30 AM to 11:30 PM

E-mail:

natlmtgs@acs.org

Posted by:

Jennifer Winston

Host:

corp.stromix.com

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