Controlled Crystallization of Organic Compounds

Crystallization of organic compounds (such as drug substances, other active ingredients, and key intermediates) is a mean used for isolation of specialty bulk products with desired quality attributes, in pharmaceutical, food, fine chemical and cosmetics industries. Control of crystallization processes is challenged commonly by both technical complexity and practical constrains. This course provides an intensive training on the fundamental principles, good practices and recent advances in this multi-disciplinary area, for solving real-world problems from early process development to product quality control in production. The basic concepts discussed in the class are related to the methods applied in process design, development and control, as well as trouble shooting. The topics in Course Outline will be discussed through a combination of lecture/discussion, use of case studies, Q&A, and problem-solving group exercises.